Jennifer R. Bellon, MD | Authors

Should Response to Preoperative Therapy Guide Local Management in Node-Positive Breast Cancer?

September 15, 2015

Current data challenge the statement that recommendations for postmastectomy radiotherapy should be based on the highest clinical or pathologic stage. Instead, data suggest that in a majority of patients, the pathologic stage after neoadjuvant chemotherapy carries more prognostic value.

ACR Appropriateness Criteria® Local-Regional Recurrence (LRR) and Salvage Surgery-Breast Cancer

February 15, 2014

Management recommendations for breast cancer local-regional recurrence (LRR), including patient scenarios, are reviewed, and represent evidence-based data and expert opinion of the American College of Radiology Appropriateness Criteria Expert Panel on LRR.

End Results of Salvage Therapy After Failure of Breast-Conservation Surgery

March 01, 2004

Drs. Lannin and Haffty’s comprehensiveand thoughtful reviewof breast cancer recurrencefollowing breast-conservingtherapy details the risk factors forlocal recurrence, factors predictive ofoutcome at the time of a breast recurrence,and prognosis after recurrence.The complex interaction betweenlocal and distant recurrence is alsoexplored; the authors argue thatlocally recurrent disease is both amarker of a more aggressive primarycancer, as well as a potential sourcefor seeding distant sites. Strategiesfor managing local recurrences arealso discussed. We are in agreementwith this excellent review and willtake this opportunity to expand on afew points.