Author | John W. Sweetenham, MD


Proposed Algorithm for Managing Ibrutinib-Related Atrial Fibrillation

November 15, 2016

Although ibrutinib-related atrial fibrillation (IRAF) occurs in up to 11% of patients in clinical trials, these studies have rarely fully characterized bleeding events or risk factors for bleeding when ibrutinib is combined with anticoagulation. Furthermore, guidelines do not provide direction regarding the preferred anti-arrhythmic agent for IRAF.

Surviving Surveillance

April 15, 2015

The message seems to be emerging that for some diseases, clinical monitoring for relapse and recurrence has a strong evidence base, is safe, and is associated with lower costs.

Treatment of Lymphoblastic Lymphoma in Adults

November 10, 2009

Lymphoblastic lymphoma (LBL) is a rare disease, comprising about 2% of all non-Hodgkin lymphomas (NHLs) in adults.[1] It is a highly aggressive subtype of lymphoma, most commonly of precursor T-cell origin, occurring most frequently in adolescents and young adults, with male predominance and frequent mediastinal, bone marrow, and central nervous system (CNS) involvement.

Hodgkin Lymphoma in Older Patients: An Uncommon Disease in Need of Study

November 15, 2008

Hodgkin lymphoma (HL) is one of the most curable malignancies in adults. However, survival rates for elderly patients with HL (often defined as ≥ 60 years of age) are inferior to those achieved by younger populations.