Paclitaxel, Carboplatin, and Radiation Therapy for Non-Small-Cell Lung Cancer
Preclinically, the taxanes appear to potentiate radiation more effectively than do the platinum compounds. In our phase I trial (LUN-17) in patients with advanced non-small-cell lung cancer, we defined the maximum tolerated
Paclitaxel and Vinorelbine in Non-Small-Cell Lung Cancer
Paclitaxel (Taxol) and vinorelbine (Navelbine) are both microtubule toxins but with opposite mechanisms of action. Paclitaxel promotes the assembly of microtubules, whereas vinorelbine prevents microtuble assembly.
2 Clarke Drive Cranbury, NJ 08512