Alex Y. Chang, MD | Authors

Recent Advances With Chemotherapy for NSCLC: The ECOG Experience

January 02, 1998

Management of disseminated non-small-cell lung cancer has changed over the past 10 years. Newer agents, such as vinorelbine (Navelbine) and paclitaxel (Taxol), have been shown to modestly improve survival in patients with

Paclitaxel and Vinorelbine in Non-Small-Cell Lung Cancer

October 02, 1997

Paclitaxel (Taxol) and vinorelbine (Navelbine) are both microtubule toxins but with opposite mechanisms of action. Paclitaxel promotes the assembly of microtubules, whereas vinorelbine prevents microtuble assembly.