- Surgical treatment for urethral carcinoma is often disfiguring. It is reasonable to offer chemoradiotherapy to patients for organ preservation.
- Due to its rarity, standard treatment paradigms for urethral carcinoma are not robustly established. Depending on the histology of the tumor, the physician can offer chemoradiation employing regimens used for urothelial or squamous cell carcinoma of the bladder.
- Regional irradiation fields should take into consideration the lymphatic drainage of the involved urethra.