Ira Winer, MD, PhD, Talks Best Data to Come Out of SGO 2022

Video

Ira Winer, MD, PhD, FACOG, spoke about which presentations during The Society of Gynecologic Oncology 2022 Annual Meeting he most enjoyed.

During The Society of Gynecologic Oncology (SGO) 2022 Annual Meeting on Women’s Cancer, CancerNetwork® spoke with Ira Winer, MD, PhD, FACOG, a gynecologic oncologist at the Karmanos Cancer Center and associate professor in the Division of Gynecologic Oncology at Wayne State University in Detroit, about the future of ovarian cancer treatment and ongoing trials that were presented at the conference that he’s eager to see results of.

Transcript:

The most interesting thing about SGO this year was the trajectory [showing] how much we’re moving towards targeted therapies and individualized therapies, even in the IO [immuno-oncology] realm, as well as the non-IO realm. If you listen, especially to some of the plenaries, you could hear that we’re really digging into the mechanistic complex of how these [tumors] work in terms of how their disease responds to these treatments. [Given that], we’ll be able to better target the cancers in the future, but also choose the right patients for the right treatment. That is the most exciting. Over the course of SGO, [presentations continually proved] how things are moving in that direction. Even in the IO realm, we had some secondary analyses of various trials to look at why perhaps patients responded versus didn’t respond. That’s going to allow us to better design our trials in the future, and also hopefully to better sequence treatments, whether it’s IO or not. That was the most exciting thing about this SGO.

Newsletter

Stay up to date on recent advances in the multidisciplinary approach to cancer.

Recent Videos
Future findings from a translational analysis of the OVATION-2 trial may corroborate prior clinical data with IMNN-001 in advanced ovarian cancer.
The dual high-affinity binding observed with ISB 2001 may avoid resistance mechanisms reported with other BCMA-targeted therapies.
The use of chemotherapy trended towards improved recurrence-free intervals in older patients with high-risk tumors as determined via the MammaPrint assay.
Use of a pharmacist-directed resource appears to improve provider confidence and adverse effect monitoring for patients undergoing infusion therapy.
Reshma L. Mahtani, DO, describes how updates from the DESTINY-Breast09, ASCENT-04, and VERITAC-2 trials may shift practices in the breast cancer field.
Co-hosts Kristie L. Kahl and Andrew Svonavec highlight what to look forward to at the 2025 ASCO Annual Meeting, from hot topics and emerging trends to travel recommendations.
Approximately 10% of patients discontinued treatment with avutometinib/defactinib due to toxicity in the phase 2 RAMP 201 trial.
Response rates appeared to be higher with avutometinib plus defactinib vs avutometinib alone in the phase 2 RAMP 201 study.
Patients who respond to avutometinib/defactinib may be maintained on treatment for long periods of time, says Rachel N. Grisham, MD.
Related Content