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|Articles|July 23, 2009

Oncology NEWS International

  • Oncology NEWS International Vol 18 No 7
  • Volume 18
  • Issue 7

M.D. Anderson group unveils new p53 marker

Houston-based investigators have identified a protein that marks the tumor suppressor p53 for destruction, providing a potential new avenue for restoring p53 in cancer cells.

Houston-based investigators have identified a protein that marks the tumor suppressor p53 for destruction, providing a potential new avenue for restoring p53 in cancer cells.

Trim24 feeds p53 to the proteasome by attaching targeting ubiquitins to the tumor suppressor. It is highly expressed in tumors and is a target of two known oncogenes in some forms of leukemia (PNAS online, June 30, 2009)

Articles in this issue

about 16 years ago

Letrozole appears less detrimental than tamoxifen to cognitive function in breast ca

about 16 years ago

Accelerated whole-breast irradiation does more with less after lumpectomy

about 16 years ago

RIBBON-1 results bolster bevacizumab as add-on to standard Rx for metastatic breast cancer

about 16 years ago

PET/CT Indicates if Early Neoadjuvant Rx is Making the Grade in Sarcoma Patients

about 16 years ago

Less is more when it comes to serial CA125 testing in ovarian cancer

about 16 years ago

Treatment varies widely in chronic myeloid leukemia

about 16 years ago

Should expectant management serve as the primary treatment option in prostate cancer?

about 16 years ago

Oncology takes blame for rising healthcare cost

about 16 years ago

Healthcare advocates call for universal coverage, acknowledge challenges

about 16 years ago

NSABP chair admits ‘failure’ in C-08 trial, denies defeat

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