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This slide show features pathology slides and PET/CT scans of prostate cancer, as well as various images of bone lesions from metastatic disease.
Slide 2: Micrograph of prostate adenocarcinoma taken by needle core biopsy, intermediate magnification. Copyright 2009 © Nephron.
Slide 4: Micrograph showing a moderately differentiated prostate cancer (Gleason 3) on the right, and less normal tissue on the left that is highly undifferentiated (Gleason 4) showing prostate cancer.
Slide 5: Prostate cancer patient with hypercalcemia and diffuse osteoblastic bone metastases. Image shows changes to spine, pelvic, and femoral bones (arrows). Copyright 2011 © Armin Kübelbeck.
Slide 6: Extensive osteoblastic metastasis of the skull in a patient with prostate cancer. This image shows the extent of metastatic tissue over the bone borders and provides a contrast enhancement of the meninges as a sign of infiltration. Copyright 2011 © Hellerhoff.
Slide 7: Micrograph of prostate adenocarcinoma with perineural invasion, conventional (acinar) type, which is the most common form of prostate cancer. Copyright 2010 © Nephron.
Slide 8: Lymphangitic carcinomatosis with metastatic prostate adenocarcinoma seen here primarily in subpleural lymphatics. Copyright 2007 © Yale Rosen.
Slide 10: Case of mucinous adenocarcinoma of the prostate: CT scan (left) shows bilateral nodules of metastatic disease. Micrograph images (right) show acinar and papillary growth patterns with pools of basophilic mucin (top) and positive coarsely granular cytoplasmic staining of the tumor cells (bottom). Copyright 2013 © Yale Rosen.
Slide 11: F-18 choline positive emission tomography (PET)/CT scan showing bone metastasis of prostate cancer. Image source: Hg6996, Wikimedia Commons.
Slide 12: Micrograph of advanced prostate carcinoma invading the seminal vesicle/ejaculatory duct. Copyright 2014 © Nephron.
Slide 13: Gross pathology image of metastatic prostate adenocarcinoma. Copyright 2014 © Yale Rosen.
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