Gustavo Dos Santos Fernandes, MD
Articles by Gustavo Dos Santos Fernandes, MD
Perioperative Treatment of Gastrointestinal Stromal Tumors
ByGustavo Dos Santos Fernandes, MD,Charles D. Blanke, MD, FACP,Daniela Freitas, MD,Rodrigo Guedes, MD,Paulo M. Hoff, MD, FACP Gastrointestinal stromal tumors (GISTs) originate from the interstitial cells of Cajal or a precursor and are the most common mesenchymal neoplasms of the gastrointestinal (GI) tract.[1] Although GISTs often present as localized masses, they are typified by a high risk of metastatic relapse, most commonly in the liver and peritoneum.
The human epidermal growth factor receptor 2 (HER2) is a transmembrane receptor with tyrosine kinase activity overexpressed in about 20% to 25% of invasive carcinomas of the breast.
