James O'Leary, MD | Authors

Taxanes in Adjuvant and Neoadjuvant Therapies for Breast Cancer

January 01, 1998

Paclitaxel (Taxol) is a diterpene originally obtained from the bark of the Pacific Yew Tree, Taxus Brevifolia. Its mechanism of action is unique. it stabilizes microtubule polymerization, thus blocking cells in the G2/M phase of