Matthew Volm, MD | Authors

SHEPHERD CENTER

Articles

Nonsteroidal and Steroidal Aromatase Inhibitors in Breast Cancer

August 01, 2001

Anastrozole (Arimidex), letrozole (Femara), and exemestane (Aromasin) are members of the third generation of aromatase inhibitors that has now replaced aminoglutethimide (Cytadren), the progestins, and tamoxifen

Taxanes in Adjuvant and Neoadjuvant Therapies for Breast Cancer

January 01, 1998

Paclitaxel (Taxol) is a diterpene originally obtained from the bark of the Pacific Yew Tree, Taxus Brevifolia. Its mechanism of action is unique. it stabilizes microtubule polymerization, thus blocking cells in the G2/M phase of