Late Lower Cranial Neuropathy in Oropharyngeal Cancer Patients
Survivors of oropharyngeal cancers who developed late lower cranial neuropathy reported having worse treatment-related symptoms.
Can ctDNA Measurements Predict DLBCL Outcomes?
A study shows pretreatment ctDNA levels and molecular responses are independently prognostic of outcomes in lymphomas.
Antiretroviral Therapy, Rituximab Active in Aids-Related DLBCL
Antiretroviral therapy and rituximab show promise in aids-related diffuse large B-cell lymphoma patients.
Vaccine Strategy Effective in Smoldering Myeloma
The PVX-410 vaccine shows immune responses in a patient population with smoldering myeloma.
Prescription Drug Coverage Key in Multiple Myeloma Therapy
A study shows prescription drug coverage leads to better survival among Medicare beneficiaries with multiple myeloma.
Phone-Based Intervention Increases CRC Screening
A study finds tailored phone intervention significantly increases colorectal cancer screening compared to usual care.
Predicting Tumor Progression in CRC Patients
It may be possible to predict personalized tumor progression in CRC patient's liquid biopsy and mathematical modeling.
Ibrutinib Common in CLL Patients Excluded from Clinical Trials
Ibrutinib demonstrated superior response rates and survival in certain CLL patients despite exclusion from major clinical trials.
Venetoclax/Obinutuzumab Effective in CLL
A study shows bendamustine followed by venetoclax and obinutuzumab was active in treatment-naive or relapsed/refractory CLL.
Advanced Practice Providers Role Growing in Oncology
The number of nurse practitioners and physician assistants in oncology is growing, according to a new study.
Postmenopausal Bleeding Common in Women With Endometrial Cancer
A meta-analysis finds that postmenopausal bleeding occurs in approximately 90% of women with endometrial cancer.
Blood Biomarker May Help Identify Those at Increased Risk for RCC
Concentrations of KIM-1 in the blood may predict for renal cell carcinoma up to 5 years prior to diagnosis.
Post-Surgical Relapse Patterns in High-Risk Non–Clear Cell RCC
Cross-sectional, long-term imaging is shown to be important for patients with high-risk resected non–clear cell RCC.
Detection of Cancer Through Exhaled Breath
VOC breath tests have potential, but more guidance, standardization are needed.
Can Preoperative Oral Care Reduce Complications From Cancer Surgery?
A retrospective study shows that undergoing oral care prior to cancer surgery decreased postoperative complications.
Bortezomib-Based Therapy Effective for Relapsed/Refractory Myeloma
Relapsed or refractory multiple myeloma patients experience high response rates, overall survival with bortezomib-based therapy.
Immunotherapy Rechallenge Successful in Some Cancer Patients
Patients treated with anti–PD-1 or anti–PD-L1 inhibitors in clinical trials were successfully retreated with the inhibitors after discontinuing the treatment.
Patients With DLBCL, FL Face Increasing Economic Burden
DLBCL and FL patients experience considerable economic burden during the first year after diagnosis.
Does Guideline-Driven Care Confer Benefit in Younger Rectal Cancer Patients?
The survival advantages associated with NCCN guideline–driven care were not realized in younger patients with stage II and stage III rectal cancer.
Resilience Important Aspect of Improved QOL for Myeloma
A high level of resilience was associated with a better mental and physical health-related quality of life among patients with multiple myeloma.
Obinutuzumab/Lenalidomide Combo Safe, Effective in Advanced Follicular Lymphoma
The combination of obinutuzumab and lenalidomide was found to be effective in relapsed or refractory follicular B-cell lymphoma.
PFS Valid Surrogate Endpoint for OS in Untreated DLBCL
New data support PFS as a surrogate endpoint for OS in future trials evaluating chemoimmunotherapy in DLBCL.
Circulating Vitamin D–Binding Protein Linked With Decreased RCC Risk
The inverse association between circulating DBP and risk of RCC support emerging evidence for an etiologic role of DBP in cancer.
Lenalidomide Consolidation Benefits CLL Patients Post Chemoimmunotherapy
Chemoimmunotherapy followed by lenalidomide consolidation is tolerated and extends PFS and OS in CLL patients.
Obesity Linked With Increased Risk of Certain Subtypes of RCC
A nested case-control study found that the association between obesity and RCC varies depending on subtype.
Pazopanib/Cetuximab Combo Promising in Recurrent, Metastatic Head and Neck Squamous Cell Carcinoma
A Washington University School of Medicine team’s findings might inform future research into inhibitors of angiogenesis and PD-1 in head and neck cancer.
Why Do Younger Colorectal Cancer Patients Have Better Outcomes Despite More Aggressive Disease?
Canadian Cancer Trials Group investigators say it's unclear if disease biology is different in younger patients or if older ones are more likely to undergo screening.
Sorafenib as Effective, Safe in Elderly RCC Patients as in Younger Ones
PFS, tumor response, and safety outcomes were similar in patient cohorts under age 75 vs those 75 years of age and older.
IKCC, German Cancer Society Issue Consensus Statement on RCC With Bone Mets
The statement emphasizes strategies for multidisciplinary care, and proposes an algorithm for clinical management of bone metastasis in RCC.
Survival Boost With Maintenance Rituxumab in Follicular Lymphoma
In addition to significant improvements in 5-year OS and PFS with maintenance rituximab, there was a trend toward an association between maintenance and reduced transformation risk.