Author | Massimo Cristofanilli, MD

Articles

CTCs and Circulating Tumor DNA for the Monitoring of Breast Cancer Patients

April 05, 2017

In this interview we discuss the use of CTCs and circulating tumor DNA for prognosis and disease monitoring in patients with breast cancer.

Is Personalized Medicine Here?

April 15, 2016

This review describes the achievements in therapeutic and molecular diagnostics, details evolving molecular platforms, and highlights the challenges for the translation of these developments to daily clinical practice.

Cancer Stem Cells: Implications for Cancer Therapy

December 15, 2014

This review will focus on properties of cancer stem cells; will compare and contrast the cancer stem cell model with the clonal evolution model of tumorigenesis; will discuss the role of cancer stem cells in the development of resistance to chemotherapy; and will review the therapeutic implications and challenges of targeting cancer stem cells, with an assessment of the potential such an approach holds for improving outcomes for patients with cancer.

Brain Metastasis in Breast Cancer: Last Barrier to the Cure?

July 12, 2012

The last two decades have seen the development of a variety of novel therapeutic agents that have improved prognoses for women with breast cancer.