Liver Transplantation for the Treatment of Hepatocellular Carcinoma
In the majority of cases, hepatocellular carcinoma develops in the setting of cirrhosis. Treatment with curative intent is possible in only 20% to 25% of cases and consists of resection or liver transplantation.
Treatment of Acute Promyelocytic Leukemia Without Cytotoxic Chemotherapy
There has been dramatic progress in the management of acute promyelocytic leukemia during the past three decades. Important insights into the pathogenesis of the disease have come to light and effective treatment has been developed.
Role of Radiation Therapy in Patients With Resectable Pancreatic Cancer
In this article, we review the data surrounding the use of chemotherapy (CT) and chemoradiotherapy (CRT) in patients with resectable pancreatic cancer.
Adverse Prognostic Features in Chronic Lymphocytic Leukemia
Our ability to stratify patients with CLL into high-risk and low-risk categories has advanced dramatically over the past two decades. However, which test or tests are most reliable remains to be seen.
Achieving Meaningful Use of Electronic Health Records for the Oncologist
In 2003, the Institute of Medicine (IOM) issued a report outlining key capabilities of an electronic health record.
Transplantation or Resection for Hepatocellular Carcinoma: Biology Determines Outcome
In their article “Liver Transplantation for the Treatment of Hepatocellular Carcinoma," Drs. Hanish and Knechtle provide a cogent review of many of the issues surrounding the management of hepatocellular carcinoma (HCC) in patients with cirrhosis.
Transplantation for Hepatocellular Carcinoma as Part of a Balanced, Multidisciplinary Strategy
Hepatocellular carcinoma (HCC) remains a formidable challenge in the United States due to its increasing incidence, its advanced-stage presentation, and its association with chronic liver disease.[1-3]
Are Prognostic Factors in CLL Overrated?
The last decade has seen major changes in the treatment of chronic lymphocytic leukemia (CLL), with randomized trials now demonstrating improved survival with the use of chemoimmunotherapy.
Radiation Therapy in Resectable/Resected Pancreatic Adenocarcinomas: Clearing Up the Fog
Surgical resection remains the sole modality that has proven capable of "curing" pancreatic cancer.
Acute Promyelocytic Leukemia Can Be Treated Successfully Without Cytotoxic Chemotherapy
In their scholarly article, Dr. Park and Dr. Tallman review the important clinical trials for treating patients with APL reported over the last two decades and argue the case for further reduction and perhaps elimination of conventional cytotoxic chemotherapy in the frontline treatment of this disease.
Arsenic Trioxide in the Management of APL: Proceed With Caution
In this excellent review of acute promyelocytic leukemia (APL) treatment, the authors highlight opportunities offered by incorporating arsenic trioxide (ATO) into the therapeutic armamentarium.
Genetic Abnormalities in CLL: Prognostic Factors-or Their Own Disease?
To find a new cure for a disease, or at least to significantly prolong patient survival, requires a bit of insight and a lot of luck.
2 Clarke Drive Cranbury, NJ 08512