ONCOLOGY Vol 25 No 8 | Oncology

Acute Promyelocytic Leukemia Can Be Treated Successfully Without Cytotoxic Chemotherapy

July 11, 2011

In their scholarly article, Dr. Park and Dr. Tallman review the important clinical trials for treating patients with APL reported over the last two decades and argue the case for further reduction and perhaps elimination of conventional cytotoxic chemotherapy in the frontline treatment of this disease.[1]

Transplantation or Resection for Hepatocellular Carcinoma: Biology Determines Outcome

July 12, 2011

In their article “Liver Transplantation for the Treatment of Hepatocellular Carcinoma," Drs. Hanish and Knechtle provide a cogent review of many of the issues surrounding the management of hepatocellular carcinoma (HCC) in patients with cirrhosis.

Treatment of Acute Promyelocytic Leukemia Without Cytotoxic Chemotherapy

July 15, 2011

There has been dramatic progress in the management of acute promyelocytic leukemia during the past three decades. Important insights into the pathogenesis of the disease have come to light and effective treatment has been developed.

Liver Transplantation for the Treatment of Hepatocellular Carcinoma

July 16, 2011

In the majority of cases, hepatocellular carcinoma develops in the setting of cirrhosis. Treatment with curative intent is possible in only 20% to 25% of cases and consists of resection or liver transplantation.