Elranatamab in Relapsed or Refractory Multiple Myeloma: Phase 2 MagnetisMM-3 Trial Results
Examine the efficacy and safety of the BCMA-targeting bispecific antibody elranatamab as monotherapy and in combinations from the Phase 2 MagnetisMM-3 trial in patients with relapsed or refractory multiple myeloma.
Guiding Through Challenges: Insights for Caregivers of R/R MM Patients
February 1st 2024Ursula Linne-Mclaren briefly discusses valuable guidance for patients and caregivers, particularly those considering bispecific therapies, providing a supportive perspective on the journey through R/R MM treatment.
Patient-Centric Care in R/R MM
February 1st 2024Nurse Linne-Mclaren provides her insights into the proactive measures, monitoring strategies, and experiences related to talquetamab-associated adverse events, along with a broader perspective on prophylactic measures for managing potential adverse events in bispecific therapies.
Consideration Factors in Treatment Selection for BTKi Therapy in R/R CLL
January 31st 2024A panel of oncology experts offer insights into key consideration factors for BTKi selection for CLL in the relapsed and refractory setting, exploring the impact of emerging MAIC data on treatment decision making.
Expert Insights on Adjuvant Immunotherapy in Unresectable Stage-III NSCLC
January 30th 2024A panel of oncology experts examine the role of consolidation immunotherapy in patients receiving concurrent chemoradiotherapy for unresectable Stage-III NSCLC, discussing 5-year survival outcomes from the PACIFIC trial, the impact on institutional treatment approaches, criteria for selecting patients for consolidation durvalumab, the significance of baseline scans, as well as exploring real-world evidence on consolidation durvalumab.
Sequential and Concurrent Chemoradiotherapy in Unresectable Stage-III NSCLC
January 30th 2024Krishna Reddy, MD, PhD, explores the roles of sequential and concurrent chemoradiotherapy (sCRT and cCRT) in patients with unresectable stage III NSCLC, delving into considerations for selecting between the two approaches and examining potential variations in treatment based on factors such as age, performance status (PS), or comorbidities.
Ide-cel or Standard Regimens in Relapsed and Refractory Multiple Myeloma
Compare outcomes between ide-cel chimeric antigen receptor T-cell (CAR-T) therapy and standard treatment regimens such as pomalidomide and daratumumab combinations in patients with heavily pretreated relapsed and refractory multiple myeloma.
Collaborative Care and Access Challenges in Managing R/R MM with GPRC5D Bispecific
January 25th 2024Oncology Clinical Pharmacist Specialist Amir Ali delves into potential challenges related to access and the use of this therapy, providing a comprehensive perspective on the complexities of incorporating GPRC5-targeting bispecifics into R/R MM patient management.
Zanidatamab Combo Appears ‘Exciting’ in HER2+/HR+ Metastatic Breast Cancer
January 25th 2024High-grade adverse effects with zanidatamab plus palbociclib and fulvestrant seem to be uncommon in patients with HER2-positive, hormone receptor–positive, metastatic breast cancer, according to Sara Hurvitz, MD, FACP.
Multiple Myeloma: Evolving Therapies and Patient Well-Being
January 23rd 2024Noa Biran, MD, addresses unmet needs in relapsed/refractory multiple myeloma, focusing on reducing treatment burden and exploring fixed-duration therapies post-transplant, and highlights potential consolidation approaches with CAR-T cells or novel agents.
Sequencing Selinexor With Novel BCMA Therapies
January 23rd 2024Noa Biran, MD, discusses the potential sequencing of selinexor with newer B-cell maturation antigen (BCMA)-directed therapies like CAR-T cells and bispecific antibodies, and explores optimizing treatment sequences to maximize efficacy, minimize resistance, and manage toxicity profiles.
Approaches to Treatment and Staging in Unresectable NSCLC
January 23rd 2024Gregory Gan, MD, briefly outlines the available treatment strategies for stage III unresectable NSCLC, and Alykhan Nagji, MD explores the characterization of patients with unresectable stage III NSCLC, underscoring the crucial role of accurate staging in guiding treatment decisions.
Treatment Strategies for NSCLC Following Progression on Adjuvant Immunotherapy
January 23rd 2024Oncology experts from the University of Kansas discuss treatment strategies for both resectable and unresectable non-small cell lung cancer (NSCLC) following progression on adjuvant immunotherapy, providing valuable insights into navigating the challenges posed by this evolving clinical scenario.
Present real-world data on the efficacy and safety of the ixazomib-lenalidomide-dexamethasone combination in patients with relapsed/refractory multiple myeloma outside of clinical trials.