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Opinion|Videos|November 14, 2023

The Role of HER2 in CRC

Author(s)Tanios S. Bekaii-Saab, MD, FACP, Daniel H. Ahn, DO, Christina S. Wu, MB, BCh, MD

Drs Cohen, Wu, and Ahn discuss HER2 in colorectal cancer, explaining that increased expression indicates possible benefit from HER2 inhibitors; Ahn summarized studies showing modest activity of dual HER2 inhibition compared to single agent trastuzumab.

Episodes in this series

Expert panel smiling at camera.

EP. 1 Overview of Colorectal Cancer (CRC)

Expert panel smiling at camera.

EP. 2 Current Treatment Options for CRC

Expert panel smiling at camera.

EP. 3 The Role of Biomarker and Molecular Testing in CRC

Expert panel smiling at camera.

EP. 4 The Role of HER2 in CRC

New treatment updates could help find more patient subtypes to target and treat in the world of CRC.

EP. 5 Multidisciplinary Care and New Treatment Options in CRC

EP. 6 Case Presentation: A 50-Year-Old Man With Metastatic CRC (mCRC)

EP. 6 Case Presentation: A 50-Year-Old Man With Metastatic CRC (mCRC)

EP. 7 Tucatinib in Patients With CRC: Data From MOUNTAINEER-01

EP. 7 Tucatinib in Patients With CRC: Data From MOUNTAINEER-01

EP. 8 Strategies for Adverse Event Management in Patients With CRC Receiving Tucatinib

EP. 8 Strategies for Adverse Event Management in Patients With CRC Receiving Tucatinib

EP. 9 MOUNAINEER-03: Tucatinib in Combination with Trastuzumab and Chemotherapy in Patients With HER2+ CRC

EP. 9 MOUNAINEER-03: Tucatinib in Combination with Trastuzumab and Chemotherapy in Patients With HER2+ CRC

EP. 10 Case Presentation: A 64-Year-Old Woman With HER2+ mCRC

EP. 10 Case Presentation: A 64-Year-Old Woman With HER2+ mCRC

EP. 11 Trastuzumab Deruxtecan in Patients with HER2+ mCRC: The DESTINY-CRC01 Trial

EP. 11 Trastuzumab Deruxtecan in Patients with HER2+ mCRC: The DESTINY-CRC01 Trial

EP. 12 Managing Interstitial Lung Disease in Patients With HER2+ mCRC Receiving Trastuzumab Deruxtecan

EP. 12 Managing Interstitial Lung Disease in Patients With HER2+ mCRC Receiving Trastuzumab Deruxtecan

EP. 13 Clinician Insights on the Treatment of Patients With CRC

EP. 13 Clinician Insights on the Treatment of Patients With CRC

EP. 14 Future Perspectives and Unmet Needs in HER2+ mCRC Treatment

EP. 14 Future Perspectives and Unmet Needs in HER2+ mCRC Treatment

EP. 15 Key Takeaways for Community Oncologists Treating Patients With HER2+ mCRC

EP. 15 Key Takeaways for Community Oncologists Treating Patients With HER2+ mCRC

EP. 16 A Variety of Treatment Options Are Becoming Available in CRC

EP. 16 A Variety of Treatment Options Are Becoming Available in CRC

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FDA Grants Fast Track Designation to Novel FLT3/CD3 Bispecific in R/R AML

Cooperative Trial Aims to Bring Precision Medicine to SCLC Subgroups

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