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Holowatyj touched on the need to learn more about the biological factors contributing to disparities in early-onset colorectal cancer and the associated burden of the disease.

Andreana N. Holowatyj, PhD, MS, Discusses Focal Questions Regarding Colorectal Cancer Disparities

Articles

A phase 3 trial found that pembrolizumab for patients with microsatellite instability–high or mismatch repair–deficient metastatic colorectal cancer significantly improved health-related quality of life compared with chemotherapy.

First-line Pembrolizumab Monotherapy Improves HRQOL Versus Chemotherapy for Metastatic Colorectal Cancer

The lead author spoke about the rising incidence of early-onset colorectal cancer, which was the focal point of her research presented at the American Association for Cancer Research Annual Meeting 2021.

Andreana N. Holowatyj, PhD, MS, on Rising Rates of Early-Onset Colorectal Cancer Worldwide

Early safety data from the RELARC trial showed complete mesocolic excision doesn’t increase intraoperative and postoperative complications of laparoscopic right hemicolectomy compared with D2 dissection when done by an experienced surgeon.

Complete Mesocolic Excision is a Safe Option in Laparoscopic Right Hemicolectomy

A new imaging technique that pairs acoustic resolution photoacoustic microscopy co-registered with ultrasound and an artificial intelligence neural network was proven feasible for use in detecting residual tumor tissue in patients with rectal cancer.

Photoacoustic Microscopy With Ultrasound Technology Is Feasible for Sensing Residual Rectal Tumors Following Surgery 

Christopher Lieu, MD, discusses the standard of care for genomic profiling in early stage CRC.

Genomic Profiling in Early CRC

Based on a single-institution study, investigators were able to correlate outcomes for unresectable colorectal liver metastases with the addition of hepatic arterial infusion pump therapy to systemic therapy to the presence of a mutation in KRAS. 

KRAS Mutations in Unresectable Colorectal Liver Metastases Linked to Reduced Response Rates 

During Colorectal Cancer Awareness month, CancerNetwork® sat down with Dorothy Dulko, PhD, to discuss social determinants of cancer. 

Dorothy Dulko, PhD, on Social Determinants of Developing Colorectal Cancer

Phyllis Morgan, PhD, sat down with CancerNetwork® to discuss health disparities during Colorectal Cancer Awareness Month. 

Phyllis Morgan on Health Disparities in Patients At Risk for Developing Colorectal Cancer

“Emerging evidence supports a possible role for overall dietary patterns that, in totality, emphasize habitually consuming fruits, vegetables, grains, and low-fat dairy and reducing red meat and alcohol intake,” wrote the study authors.

Colorectal Cancer | Topics