Epithelioid Sarcoma: Overview and Presentation
Panelists discuss how understanding the epidemiology, clinical presentation, and metastatic patterns of epithelioid sarcoma (ES) can support earlier recognition, accurate diagnosis, and more effective multidisciplinary management of this rare and aggressive soft tissue tumor.
Summary for Physicians: Epidemiology and Landscape of Epithelioid Sarcoma (ES)
Epithelioid sarcoma (ES) is a rare, aggressive soft tissue sarcoma that primarily affects adolescents and young adults, with a slight male predominance. It most often arises in the distal extremities but can also occur in proximal areas, which may complicate diagnosis. ES is known for its high rates of local recurrence and potential for both regional lymph node involvement and distant metastasis, particularly to the lungs. Due to its rarity and variable presentation, ES poses significant diagnostic and therapeutic challenges, emphasizing the importance of early recognition and multidisciplinary care.
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