Optimizing the Care Pathway for Advanced Epithelioid Sarcoma: Diagnosis, Treatment, and Beyond

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Panelists discuss how enhancing diagnostic accuracy, optimizing multidisciplinary care, and advancing treatment strategies—including targeted therapies—can improve outcomes and decision-making in patients with advanced epithelioid sarcoma (ES).

EP. 1: Epithelioid Sarcoma: Overview and Presentation

Neeta Somaiah, MD;Edwin Choy, MD, PhD;Brian Rubin, MD, PhD

April 18th 2025

Panelists discuss how understanding the epidemiology, clinical presentation, and metastatic patterns of epithelioid sarcoma (ES) can support earlier recognition, accurate diagnosis, and more effective multidisciplinary management of this rare and aggressive soft tissue tumor.

EP. 2: Epithelioid Sarcoma: Histological Features and Differential Diagnoses

Neeta Somaiah, MD;Edwin Choy, MD, PhD;Brian Rubin, MD, PhD

April 18th 2025

Panelists discuss how recognizing the distinct histological patterns and the hallmark loss of INI1 expression in epithelioid sarcoma (ES) can enhance diagnostic precision, inform prognosis, and guide emerging targeted therapeutic strategies.