|Articles|August 1, 2008

Oncology NEWS International

  • Oncology NEWS International Vol 17 No 8
  • Volume 17
  • Issue 8

Erbitux gains expanded approval in Europe

Cetuximab (Erbitux) has received broader approval in the European Union as a first-line treatment for metastatic colorectal cancer.

Cetuximab (Erbitux) has received broader approval in the European Union as a first-line treatment for metastatic colorectal cancer. Erbitux can now be used in European patients with EGFR-expressing, KRAS wild-type metastatic colorectal cancer in combination with chemotherapy and also as a single agent in patients who have failed oxaliplatin (Eloxatin)-based and irinotecan (Camptosar)-based therapy, according to manufacturer Merck KGaA of Darmstadt, Germany.

European Commission approval was based on data from two randomized, controlled trials. In the phase III CRYSTAL study, patients with KRAS wild-type tumors had a 59% response rate with cetuximab/chemotherapy vs 43% for chemotherapy alone. In the phase II OPUS trial, response rates were 61% vs 37%, respectively.

Articles in this issue

almost 18 years ago

An editor says farewell

almost 18 years ago

High cost of biologics takes a toll on hem/onc practices

almost 18 years ago

FDA mandates changes to ESA labeling info

almost 18 years ago

Poll results: Medical education falters on pain relief

almost 18 years ago

Certification offered to rad oncs for care of dying patients

almost 18 years ago

VA enlists ACR for RT accreditations; H&N date change

almost 18 years ago

Docs deserve pay for cognitive skill set

almost 18 years ago

Creator of Herceptin goes Hollywood in TV biopic

almost 18 years ago

Avastin/sunitnib RCC trial closes after serious toxicities

almost 18 years ago

FDA cracks down on counterfeit cancer cure products

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