Jeffrey Wolf, MD, on Implications of Findings from Multiple Myeloma Study Presented at ASH

Wolf touched on the implications of results from a study investigating outcomes when making clinical decisions based on the MRD status of patients with multiple myeloma.

Jeffrey Wolf, MD, of the University of California San Francisco, discussed with CancerNetwork the implications of the results from a study investigating outcomes when making clinical decisions based on the MRD status of patients with multiple myeloma presented at the 2020 American Society of Hematology (ASH) Annual Meeting.


So, what we discovered when we looked at those 58 people who had decisions made, and we compared it to the other patients where decisions weren’t made, we found that there were more people that achieved MRD-zero because the change allowed them to get to MRD-zero. And, for patients [where] their decision was controlled longer, that is the progression-free survival, improved significantly from 75 months to 97 months. So, we believe that by measuring MRD and using it to make decisions, you can achieve better outcomes for your patient.

Related Videos
Current clinical trials look to assess 177Lu-PSMA-617 in combination with other therapies including androgen deprivation therapy and docetaxel.
An expert from Dana-Farber Cancer Institute indicates that patients with prostate cancer who have 1 risk factor should undergo salvage radiotherapy following radical prostatectomy before their prostate-specific antigen level rises above 0.25 ng/ml.
Experts on multiple myeloma
Experts on multiple myeloma
An expert from Weill Cornell Medicine highlights key clinical data indicating the benefits of radium-223 in the treatment of patients with metastatic castration-resistant prostate cancer.
The risk of radionuclide exposure to the public reflects one reason urologists need to collaborate with radiation oncologists when administering radiopharmaceuticals to patients with prostate cancer.
Switching out beta emitters for alpha emitters, including radium-223, is one way to improve radiopharmaceutical treatment of prostate cancer, according to an expert from Weill Cornell Medicine.
Data demonstrate the feasibility of automated glomerular filtration rate prediction to decide between partial nephrectomy and radical nephrectomy in kidney cancer, according to an expert from the Cleveland Clinic.
Early phase trials investigating cellular therapies, bispecific antibodies, and antibody-drug conjugates for refractory kidney cancer may uncover strategies to overcome resistance mechanisms.
Experts on multiple myeloma
Related Content