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This slide show features various images of papillary, clear cell, chromophobe, and tubulocystic renal cell carcinoma.
Slide 1: This 8-cm carcinoma of the lower pole of the kidney shows extension beyond the cortical surface, but it does not infiltrate the perinephric adipose tissue. Microscopically, it is a clear cell renal cell carcinoma (RCC).
Slide 2: Micrograph of a clear cell RCC, intermediate magnification, H&E stain. The tumor has a Fuhrman nuclear grade of 3. Copyright 2014 © Nephron.
Slide 4: Micrograph of a type 1 papillary RCC, intermediate magnification, H&E stain. Copyright 2014 © Nephron.
Slide 5: Micrograph of a type 1 papillary RCC, high magnification, H&E stain. Copyright 2014 © Nephron.
Slide 7: Multinodular RCC metastasis in the lower respiratory tract. The abundant fat content of the primary tumor imparts a yellow appearance to the metastatic nodules.
Slide 9: Micrograph of a tubulocystic RCC, also known as tubulocystic carcinoma of the kidney, intermediate magnification, H&E stain. Copyright 2015 © Nephron.
Slide 10: Micrograph of a tubulocystic RCC, very high magnification, H&E stain. Copyright 2015 © Nephron.
Slide 11: Gross pathology of bisected kidney showing large RCC. Much of the kidney has been replaced by gray and yellow tumor tissue. A little remaining renal cortex and pericapsular fat are visible at the bottom of this surgical specimen.
Slide 12: HDP whole-body bone scan. Patient has renal cancer with several bone metastases in the vertebral column, which are basically invisible. Image source: Wikimedia Commons, Hg6996.
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