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Prostate Cancer

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ROCKVILLE, Md-The Center for Prostate Disease Research (CPDR) has opened a new freestanding research center to consolidate its many initiatives and allow these programs to continue to develop and expand. The new site is the nation’s only facility dedicated solely to prostate disease research.

Doctors have suspected that radiation therapy helps prevent patients from dying of prostate cancer, but they had little scientific evidence to support that theory. Now, Richard Valicenti, MD, assistant professor of radiation oncology at Jefferson

NEW YORK-When cancer patients go to the Internet for information on their disease, they are often overwhelmed by the thousands of sources available. The new Prostate Cancer Treatment Guidelines for Patients, issued jointly by the American Cancer Society (ACS) and the National Comprehensive Cancer Network (NCCN), “is an attempt to give patients a structure for processing information,” said Rodger Winn, MD, of M.D. Anderson Cancer Center and a key player in the NCCN guidelines development. The NCCN is an alliance of 17 of the nation’s leading cancer centers.

PHILADELPHIA-Lycopene, the phytonutrient that produces the red color in tomatoes, showed beneficial effects on the prostate cancers of a group of men scheduled for prostatectomy, researchers reported at the American Association for Cancer Research annual meeting.

ASCO-A leuprolide (Lupron) implant that provides continuous testosterone suppression for up to a year has been shown to be safe and effective in patients with advanced prostate cancer. The experimental implant spares patients the need for frequent injections of the LHRH (luteinizing hormone-releasing hormone) agonist.

ASCO-Docetaxel (Taxotere) plus estramustine phosphate (Emcyt) and low-dose hydrocortisone proved effective and well tolerated in a phase II study of men with hormone-refractory prostate cancer. The study was conducted by the Cancer and Leukemia Group B (CALGB) and presented at the ASCO annual meeting.

DALLAS-The American Urological Association is one of the premier specialist medical associations and has done a great deal to advance patient care in this field. I know the AUA works closely with AFUD, the American Foundation for Urological Diseases, and I have a great appreciation for the work you do. Although I’m not a doctor or a scientist, I’m working with you to accomplish some of the same objectives.

NEW YORK--The National Comprehensive Cancer Network (NCCN) and the American Cancer Society (ACS) have collaborated to translate the NCCN prostate cancer guidelines into a patient-friendly resource for appropriate treatment, the two organizations announced at a press briefing.

DALLAS-An analysis of SEER data shows small but steady decreases in prostate cancer mortality since 1991, Robert A. Stephenson, MD, said at the American Urological Association annual meeting. He attributed the decline to a combination of factors, including earlier detection and better treatment of advanced disease. Yet overall, he said, the data show that prostate cancer remains a major cause of death in men and may be undertreated in the elderly.

New research shows that a low-calorie diet slows the progress of prostate cancer in animals. Tumor progression was inhibited irrespective of how the calories were reduced; ie, by cutting fat or carbohydrates or by changing the overall diet. The research

The VA Cancer of the Prostate Outcomes Study (VA CaPOS) is collecting quality-of-life (QOL) information from prostate cancer patients, spouses, and physicians at six VA medical centers. Currently, 601 men with prostate

DALLAS-Of 1,371 men with early-stage prostate cancer (T1c) detected by PSA screening and treated via radical prostatectomy between 1987 and 1996, only three have died of their cancer, Angelo J. Iocca, MD, of the Mayo Clinic, Rochester, Minnesota, said at the American Urological Society annual meeting.

BETHESDA, Md-Up to 40% to 50% of prostate cancer patients who undergo radical prostatectomy for localized prostate carcinomas will relapse. Traditional prognostic markers, such as clinical stage or pretreatment levels of prostate-specific antigen (PSA), are of limited value in predicting which individuals will have relapsed disease.

New Orleans-The advisability of neoadjuvant hormonal therapy in the management of prostate cancer is a hotly debated issue. At the American Society of Therapeutic Radiology and Oncology (ASTRO) spring refresher course, two opinion leaders in radiation oncology squared off on opposite sides of this issue.

BETHESDA, Md-The National Cancer Institute is funding a wide range of prostate cancer research, including genetic epidemiology, molecular diagnostics, diet and nutrition, animal models, surveillance, diagnostic imaging, clinical trials, prevention and early detection, and the Cancer Genome Anatomy Project .