Which Rectal Cancers Are Locally Advanced?August 20th 2012
In populations in whom there has been a focus on the important components of rectal cancer management, 5-year survival is better in rectal cancer than in colon cancer, which was not the case in the past. Total mesorectal excision (TME) is one of many important components of current management.
The Key to Reducing Quackery Lies in Healing Patients and Treating Their ExperienceAugust 20th 2012
If doctors were trained in communication skills, then quackery would diminish greatly. When you are told what day you are going to die and all hope is taken away, why not seek alternative therapies?
Quackery, Placebos, and Other Thoughts: An Integrative Oncologist’s PerspectiveAugust 20th 2012
As they say, “absence of evidence is not evidence of absence.” Many alternative therapies, once believed by conventional medical practitioners to be merely placebos, have now been shown to have proven therapeutic value (eg, acupuncture, numerous botanical extracts, meditation).
Going Beyond Systemic Fluoropyrimidines With Radiation Therapy for Rectal Cancer: What Should Be the Priority?August 20th 2012
As we look forward, we suggest that the priority should be to further our understanding of the tumor’s interactions with its microenvironment and with the immune system. We think that such an understanding will be critical for advances in locally advanced rectal cancer therapy.
Cancer Quackery: The Persistent Popularity of Useless, Irrational 'Alternative' TreatmentsAugust 20th 2012
This review provides a brief recap of the history of medical quackery and an overview of the various types of unproven or disproved cancer therapies popular now in the United States and elsewhere.
Current Perspectives on Preoperative Integrated Treatments for Locally Advanced Rectal Cancer: A Review of Agreement and ControversiesAugust 20th 2012
The preferred integrated treatment modality for locally advanced rectal cancer is preoperative radio(chemo)therapy followed by total mesorectal excision, though certain aspects of this standard are still debated.
The Natural History of Hormone Receptor–Positive Breast Cancer: Attempting to Decipher an Intriguing ConceptAugust 10th 2012
It is time to develop more active treatments in the early-disease setting that actually eradicate ER-positive breast cancer before new mutations and secondary resistance have a chance to develop. In this regard, standard chemotherapy is not the answer.