Author | Vincenzo Valentini, MD

Articles

MRI-Based Treatment Decision Making for Rectal Cancer

August 15, 2014

ByBruce D. Minsky, MD|Vincenzo Valentini, MD

There are a number of clinicopathologic variables that predict outcome in rectal cancer. In the era of postoperative chemoradiation treatment, these were more easily identified and were used to help select patients for adjuvant therapy.

Current Perspectives on Preoperative Integrated Treatments for Locally Advanced Rectal Cancer: A Review of Agreement and Controversies

August 20, 2012

ByFrancesco Cellini, MD|Vincenzo Valentini, MD

The preferred integrated treatment modality for locally advanced rectal cancer is preoperative radio(chemo)therapy followed by total mesorectal excision, though certain aspects of this standard are still debated.

One for All or One for One?

June 01, 2008

ByVincenzo Valentini, MD|Maria Antonietta Gambacorta, MD

The authors review the main evidence from the literature on neoadjuvant approaches in locally advanced rectal cancer, starting with the use of radiotherapy only in the pre–total mesorectal excision (TME) era, through fluorouracil (5-FU)–based chemoradiation in the TME era, to the most modern administration of “targeted therapy” in association with radiotherapy and traditional chemotherapy.