ONCOLOGY Vol 26 No 9 | Oncology

Improving Radiotherapy After Breast-Conserving Surgery

September 13, 2012

In assessing the value of innovations in breast cancer radiotherapy, it is important to consider not only the basis of their impact on mortality, local recurrence, and cosmesis; emphasis should also be placed on factors such as treatment tolerance, convenience, and delayed morbidities.

Limited-Field and Whole-Breast Hypofractionated Radiotherapy

September 13, 2012

With the publication of mature experiences using accelarated partial breast irradiation (APBI) and accelerated whole breast irradiation (AWBI), the use of shortened courses of radiotherapy has become increasingly popular.

Irradiation in Early-Stage Breast Cancer: Conventional Whole-Breast, Accelerated Partial-Breast, and Accelerated Whole-Breast Strategies Compared

September 13, 2012

Given their greater convenience and, in most cases, decreased costs, APBI and AWBI are becoming increasingly popular alternatives to conventional WBI for early-stage breast cancer patients who desire BCT. However, given the protracted time to local recurrence and complications following BCT, definitive results from randomized clinical trials comparing conventional WBI vs AWBI or APBI are limited.

ALL in Adults: How Can We Do Better?

September 12, 2012

The most interesting developments in drug therapy for adult ALL are occurring in two fields: (1) molecularly targeted therapies and (2) the use of antibodies, conjugated antibodies, or antibody constructs.

Treatment of Adult ALL: More Questions Than Answers

September 12, 2012

It is clear that the management of adult patients with ALL is an area in which little progress has been made in the last 30 years. Given the disappointing outcomes, the field is one that lends itself to the study of the incorporation of novel agents, including monoclonal antibodies and tyrosine kinase and proteasome inhibitors, as well as to further study of allogeneic transplant.

Using Social Media in Oncology for Education and Patient Engagement

September 12, 2012

We presented an interactive session entitled “Using Social Media in Oncology for Education and Patient Engagement” at the American Society of Clinical Oncology (ASCO) 2012 Annual Meeting. This article summarizes the points made in those presentations.

Sphincter Preservation in the Treatment of Locally Advanced Rectal Cancers

September 12, 2012

To the Editor: We appreciated the commentaries by Drs. Duda, Glimelius, and Willet on our paper “Current Perspectives on Preoperative Integrated Treatments for Locally Advanced Rectal Cancer: A Review of Agreement and Controversies” (August issue of ONCOLOGY).

Personalized Medicine: Medicine for the Privileged?

August 21, 2012

“Personalized medicine” holds its promise only at the substantial cost of widespread use of the awesome tools of molecular science, and at a time of intense scrutiny of the costs and benefits of medical treatments, can we really afford it?

New ASCO, SSO Guidelines for Sentinel Lymph Node Biopsy in Melanoma

August 17, 2012

Sentinel lymph node biopsy is recommended for patients with newly diagnosed intermediate-thickness melanomas, while the procedure may not be indicated for patients with thinner lesions, according to a new set of guidelines.

Is Diagnosing Cancer With a Smartphone in Our Future?

June 01, 2012

The proposition that a consumer smartphone could somehow become part of the diagnostic toolkit of an oncologist may seem ridiculous. There are, however, many researchers and start-ups that would disagree.