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|Articles|June 19, 2009

Oncology NEWS International

  • Oncology NEWS International Vol 18 No 6
  • Volume 18
  • Issue 6

Abraxis backs SPARC as prognostic biomarker

SPARC (secreted protein acidic and rich in cysteine) may play a role in tumor growth and angiogenesis, according to preclinical data presented at AACR 2009.

SPARC (secreted protein acidic and rich in cysteine) may play a role in tumor growth and angiogenesis, according to preclinical data presented at AACR 2009.

Researchers at Abraxis BioScience, the manufacturer of Abraxane (nab-paclitaxel), found that recombinant human SPARC grown in vitro fostered angiogenesis and the development of mature blood vessels. SPARC may play a greater role in the angiogenic process beyond initiating the growth of new blood vessels, they said (abstracts 1478, 2572, 3769, 4017, 5168).

Articles in this issue

over 16 years ago

ADT in prostate ca increases risk of bone and heart complications

over 16 years ago

ALK-1 receptor: New target in angiogenesis

over 16 years ago

Abraxane prolongs PFS in metastatic disease

over 16 years ago

SAVI applicator removes obstacles associated with brachytherapy

over 16 years ago

Mistrust, costs reduce breast cancer screening among minorities

over 16 years ago

Oral chemotherapy poses more challenges for cancer community

over 16 years ago

CMS nixes CT colonography screening

over 16 years ago

New ultrasound strategy helps pinpoint prostate tumors

over 16 years ago

New research on VEGF, gene mutations refines understanding of tumor angiogenesis

over 16 years ago

From the ONI archives: Should low-dose induction dexamethasone be standard of care in multiple myeloma?

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