Neck Mass Found in 45-Year-Old Man

Poll

A 45-year-old man presents with a mass in the right neck. After the biopsy is performed, what is your diagnosis?

A 45-year-old man presents with a mass in the right neck. According to the pathology slide below, what is your diagnosis?

What is your diagnosis?

A. Leiomyosarcoma
B. Desmoid tumor
C. Spindle cell lipoma
D. Squamous cell carcinoma

Newsletter

Stay up to date on recent advances in the multidisciplinary approach to cancer.

Subscribe Now!
Recent Videos
The phase 3 NIVOSTOP trial evaluated an anti–PD-1 immunotherapy, nivolumab, in a patient population similar in the KEYNOTE-689 trial.
Opportunities to further reduce relapses include pembrolizumab-based combination therapy and evaluating the agent’s contribution before and after surgery.
For patients with locally advanced head and neck cancers, the current standard of care for curative therapy has a cure rate of less than 50%.
Treatment with toripalimab does not yield the same vascular toxicity seen with pembrolizumab in patients with advanced or metastatic nasopharyngeal carcinoma, according to Barbara Burtness, MD.
Overall survival also appears to improve with toripalimab compared with chemotherapy among patients with metastatic or advanced nasopharyngeal carcinoma.
head and neck cancer
head and neck cancer
Related Content
Adjuvant Nivolumab/Cisplatin/RT Improves DFS in Advanced Head and Neck Cancer

Adjuvant Nivolumab/Cisplatin/RT Improves DFS in Advanced Head and Neck Cancer

Ariana Pelosci
June 1st 2025
Article

Results from the NIVOPOSTOP trial found improved DFS with adjuvant nivolumab plus cisplatin and RT for patients with LA-SCCHN.

David Sher on the Updated ASTRO Guidelines for Oropharyngeal Cancer

David Sher on the Updated ASTRO Guidelines for Oropharyngeal Cancer

David J. Sher, MD, MPH
September 15th 2017
Podcast

In this interview we discuss new clinical guidelines from ASTRO on the use of radiotherapy in treating oropharyngeal cancer.

Efti plus pembrolizumab demonstrated no new safety signals in the TACTI-003 trial.

Frontline Efti Combo Yields Meaningful Survival in PD-L1–Low HNSCC

Russ Conroy
May 8th 2025
Article

Survival data with eftilagimod alfa plus pembrolizumab compare favorably with historical results seen with standard-of-care therapies in this population.

Event-free survival events were observed in 37.5% of patients taking pembrolizumab vs 45.3% without among patients with resectable locally advanced HNSCC.

Perioperative Pembrolizumab Enhances Survival in Locally Advanced HNSCC

Ashley Chan
April 30th 2025
Article

Event-free survival events were observed in 37.5% of patients with resectable locally advanced HNSCC who took pembrolizumab vs 45.3% in those who did not.

Data from the phase 3 AK105-304 study support the approval of penpulimab in this nasopharyngeal carcinoma population.

FDA Approves Penpulimab in Non-Keratinizing Nasopharyngeal Carcinoma

Roman Fabbricatore
April 24th 2025
Article

Data from the phase 3 AK105-304 study support the approval of penpulimab in this nasopharyngeal carcinoma population.

Advancing Biomedical Research on Salivary Antioxidants: Exploring the Significance in Oral Precancer and Cancer

Advancing Biomedical Research on Salivary Antioxidants: Exploring the Significance in Oral Precancer and Cancer

Vidya G Doddawad, BDS, MDS;B.M. Gurupadayya;Vidya CS;Shivananda S, BDS, MDS;Karthikeya Patil;R. Sumukh Bharadwaj
April 16th 2025
Article

Human saliva may hold antioxidants that are able to monitor the oral cavity's oxidative processes and offer guidance for the development of new drugs.