Salma K. Jabbour, MD, Discusses the Value of Treating Patients With NSCLC in a Multidisciplinary Setting

Video

Jabbour detailed the importance of managing care in a multidisciplinary setting for patients enrolled in the KEYNOTE-799 trial with stage III NSCLC.

CancerNetwork® sat down with Salma K. Jabbour, MD, of the Rutgers Cancer Institute of New Jersey, to discuss how patients with stage III non–small cell lung cancer (NSCLC) treated on the phase 2 KEYNOTE-799 trial (NCT03631784) that was presented at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting can benefit from a multidisciplinary approach to care.

In the trial, patients with unresectable, locally advanced NSCLC were treated with pembrolizumab plus platinum doublet chemotherapy and radiotherapy followed by pembrolizumab monotherapy.

Transcription:

It's really important for [patients with stage III NSCLC] to be evaluated in a multidisciplinary setting and to be managed in a multidisciplinary setting and it is very much a team approach from the onset of the patient's care. I think that really can't be underestimated because these patients require a lot of attention and care to make sure that their treatment really goes smoothly and [adverse] effects from chemoradiation can be managed, such as esophagitis, dermatitis, and pneumonitis. That is really an important component. The communication with the team, both from the medical oncologist, the radiation oncologist, and initial involvement from the surgeon make the determination about resectability. All of it is really important and helps to carry the patient through with a tolerable toxicity profile and…have them achieve a successful and manageable therapy.

Reference

Jabbour SK, Lee H, Frost N, et al. KEYNOTE-799: Phase 2 trial of pembrolizumab plus platinum chemotherapy and radiotherapy for unresectable, locally advanced, stage 3 NSCLC. J Clin Oncol. 2021;39(suppl 15):8512. doi:10.1200/JCO.2021.39.15_suppl.8512.

Related Videos
Pegulicianine-guided breast cancer surgery may allow practices to de-escalate subsequent radiotherapy, says Barbara Smith, MD, PhD.
Adrienne Bruce Shannon, MD, discussed ways to improve treatment and surgical outcomes for patients with dMMR gastroesophageal cancer.
Barbara Smith, MD, PhD, spoke about the potential use of pegulicianine-guided breast cancer surgery based on reports from the phase 3 INSITE trial.
Patient-reported symptoms following surgery appear to improve with the use of perioperative telemonitoring, says Kelly M. Mahuron, MD.
Treatment options in the refractory setting must improve for patients with resected colorectal cancer peritoneal metastasis, says Muhammad Talha Waheed, MD.
Although immature, overall survival data from the KEYNOTE-868 trial may support the use of pembrolizumab plus chemotherapy in patients with endometrial cancer.
Dostarlimab plus chemotherapy appears to yield favorable overall survival in patients with mismatch repair proficient endometrial cancer.
Some patients with large B-cell lymphoma may have to travel a great distance for an initial evaluation for CAR T-cell therapy.
Brian Slomovitz, MD, MS, FACOG discusses the use of new antibody drug conjugates for treating patients with various gynecologic cancers.
Education is essential to referring oncologists manage toxicities associated with CAR T-cell therapy for patients with large B-cell lymphoma.
Related Content