
Selecting first-line therapy for advanced clear cell renal cell carcinoma (RCC) increasingly starts with a choice between dual immunotherapy and an immunotherapy plus tyrosine kinase inhibitor (TKI) combination.

Selecting first-line therapy for advanced clear cell renal cell carcinoma (RCC) increasingly starts with a choice between dual immunotherapy and an immunotherapy plus tyrosine kinase inhibitor (TKI) combination.

The CLEAR trial established lenvatinib plus pembrolizumab as a frontline option in advanced RCC.