The patient is a 26-year-old woman with a complex oncologic history. At 1 year of age, she was diagnosed with a stage III abdominal neuroblastoma, which was treated, and again at age 9, she had a recurrence of neuroblastoma in the left axilla. She was in her usual state of good health until 18 months ago, when she presented with hematuria and was found to have a right-sided kidney mass.
Brian Kavanagh, MD
patient is a 67-year-old male with mild obstructive symptoms and an American Urology Association symptom score of 8. He was noted to have a prostate-specific antigen (PSA) level of 3.2 ng/mL. Because this represented a significant increase in his PSA velocity (rate of change over time), he proceeded to have a biopsy, which was positive for prostate cancer. He has no other complaints and visits us for an opinion on the treatment of his prostate cancer.
Quan and colleagues have provided
an important and timely
review on the treatment of
brain metastases in patients with small
cell lung cancer (SCLC). We certainly
agree with the comments and views
of the authors, but wish to emphasize
several aspects of central nervous
system (CNS) metastases in SCLC