Author | Derek Raghavan, MD, PhD, FACP, FRACP, FASCO


Big Data: Not Really the Same as Level 1 Data

January 15, 2015

The problem with large sets of data is the risk of the “GIGO” principle-viz. garbage in, garbage out-and it requires a very careful and thoughtful investigator to rule out the many errors of large-scale data capture.

In Germ Cell Cancer, Are We at the End of the Chemotherapy Era? No-Targeted Therapies Have Not Heralded Its Demise

November 15, 2013

Germ cell tumors (GCT) are an exemplar of the successful use of chemotherapy and of the successful interplay of phase II and phase III trials. The biggest contributor to cure in metastatic GCT is cisplatin-based chemotherapy, unchallenged after more than 30 years.

Remembering Old Lessons in Prostate Cancer: Avoiding Errors 'in PARPituity'

July 15, 2013

The “experts” should maintain a stringent standard regarding what merits further development and reconsider carefully and critically the available data before committing to PARP inhibition, attacks on the PI3K pathway, and vasoactive agents in prostate cancer.