Paclitaxel and Carboplatin as First-Line Chemotherapy for Advanced Breast Cancer
ByGeorge Fountzilas, MD,Dimitrios Bafaloukos, MD,Gerasimos Aravantinos, MD,Constantine Nicolaides, MD,Haralambos Kalofonos, MD,Pavlos Papakostas, MD,Nicholaos Xiros, MD,Evalgelia Razi, MD
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In a phase II study, 66 patients with advanced breast cancer (median age 56 years; range, 28 to 75 years) were treated with paclitaxel (Taxol), 175 mg/m² infused over 3 hours, and carboplatin (Paraplatin), dosed to attain an