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| Optimizing Outcomes in Patients with HER2+ Metastatic Breast Cancer

IASLC North America Conference on Lung Cancer

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Phase III CANOPY Studies to Investigate Canakinumab in NSCLC

Phase III CANOPY Studies to Investigate Canakinumab in NSCLC

Seth Augenstein
October 15th 2019

The agent has a high affinity and specificity for interleukin-1 beta.


Pembrolizumab Shows Benefit for NSCLC Patients with Brain Metastases

Pembrolizumab Shows Benefit for NSCLC Patients with Brain Metastases

Seth Augenstein
October 15th 2019

The results showed that even patients with disease that has spread to the brain should be considered for immunotherapy.


Neutrophil-to-Lymphocyte Ratio Helps Predict Survival in Stage III NSCLC

Neutrophil-to-Lymphocyte Ratio Helps Predict Survival in Stage III NSCLC

Seth Augenstein
October 12th 2019

NLR appeared to be a significant predictor of overall survival, and also showed a trend in favor of progression-free survival, among patients with stage III locally-advanced non-small cell lung cancer.


Sequential TKI Treatment Improves OS in EGFR T790M-Positive NSCLC

Sequential TKI Treatment Improves OS in EGFR T790M-Positive NSCLC

Seth Augenstein
October 12th 2019

Sequential afatinib and osimertinib improved median overall survival by almost 3.5 years in patients with EGFR T790M-positive non-small cell lung cancer, with an even greater benefit seen in those with Del19-positive disease.


Metformin Increases Glucose Uptake in Early-Stage NSCLC

Metformin Increases Glucose Uptake in Early-Stage NSCLC

Seth Augenstein
October 12th 2019

Metformin appeared to increase glucose uptake in lung cancer cells, according to results from a phase II trial.

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