|Articles|February 1, 2008

Oncology NEWS International

  • Oncology NEWS International Vol 17 No 2
  • Volume 17
  • Issue 2

Exelixis/BMS to develop XL139, hedgehog pathway inhibitor

Exelixis, Inc. and Bristol-Myers Squibb Company will collaborate to co-develop and co-commercialize Exelixis' compound XL139, a small molecule inhibitor of the hedgehog pathway, in the United States.

SOUTH SAN FRANCISCO, California—Exelixis, Inc. and Bristol-Myers Squibb Company will collaborate to co-develop and co-commercialize Exelixis' compound XL139, a small molecule inhibitor of the hedgehog pathway, in the United States. Hedgehog plays a critical role in regulating cell growth, proliferation, and differentiation, and is deregulated in a variety of cancers, making it a promising target for cancer therapies, Exelixis said.

Articles in this issue

over 18 years ago

NLST article not balanced, critic of screening trial asserts

over 18 years ago

M.D. Anderson and AstraZeneca form neuropathic pain alliance

over 18 years ago

Good nilotinib responses in imatinib-resistant AP-CML

over 18 years ago

Virus linked to Merkel cell carcinoma

over 18 years ago

Benefit of adjuvant RT/CT for pancreatic ca affirmed

over 18 years ago

Recurrence Score helps select node+ pts for chemo

over 18 years ago

For resectable liver mets: Preop chemotherapy or not?

over 18 years ago

Plerixafor boosts stem cell mobilization in myeloma pts

over 18 years ago

MRI shows second-hand smoke damage

over 18 years ago

Assay has high sensitivity for hard-to-detect SLN mets

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