Judy Ou, PhD, on Fine Particulate Matter in Pediatric and AYA Patients with Cancer

Article

The research scientist spoke about the study that found that fine particulate matter pollution was associated with mortality in pediatric, adolescent, and young adult patients with specific cancers.

In an interview with CancerNetwork®, Judy Ou, PhD, research scientist at the Huntsman Cancer Institute at the University of Utah, discussed the study of fine particulate matter pollution in pediatric, adolescent, and young adult patients. 

The study, published in Cancer Epidemiology, Biomarkers & Prevention, found that fine particulate matter pollution was associated with mortality in pediatric, adolescent, and young adult patients with specific cancers. 

“Fine particulate matter is called ‘fine’ because of its incredibly small size. And so, these are small particles that are less than 2.5 micrometers in diameter,” explained Ou. “The reason that they are concerning to human health is that they can be inhaled into the lungs and are capable of crossing into the bloodstream.” 

“Fine particulate matter has been linked to a wide variety of health effects amongst humans, including mortality, cancer incidence, and also lung and heart disease in the general public,” Ou continued.

As of now, air quality policies to mitigate this issue have not been enforced at local, state, and federal levels. According to Ou, it is important that patients and their caregivers understand the complications related to fine particulate matter so that they may become informed advocates to support enforcing these policies.

“What we really should be doing is thinking through how, basically, general policy changes can affect a potentially vulnerable population and a population that already has a lot of issues and problems,” Ou said. “If we can do anything to alleviate some of those potential risk factors for bad outcomes then we should probably try to do that.”

This segment comes from the CancerNetwork® portion of the MJH Life Sciences National Broadcast, airing daily on all MJH Life Sciences channels.

Reference:

Ou JY, Hanson HA, Ramsay JM, et al. Fine Particulate Matter Air Pollution and Mortality Among Pediatric, Adolescent, and Young Adult Cancer Patients. Cancer Epidemiol Biomarkers Prev. doi:10.1158/1055-9965.EPI-19-1363.

Newsletter

Stay up to date on recent advances in the multidisciplinary approach to cancer.

Recent Videos
“Everyone—patients, doctors—we all want the same thing. We want [patients] to live longer,” said Kiran Turaga, MD, MPH, on patients with peritoneal surface malignancies.
Data from the phase 3 DeLLphi-304 trial at ASCO 2025 revealed a survival advantage with tarlatamab vs chemotherapy in second-line ES-SCLC.
The new peritoneal surface malignancy care guidelines had clinicians gather from every disease state to show increased representation.
The FDA approval of tarlatamab in SCLC has received much press attention, according to Daniel R. Carrizosa, MD, MS.
These new guidelines aim to alleviate some of the problems caused by patients with peritoneal metastases being diagnosed with the disease in late stages.
A combined cohort composed of patients from the TROPION-Lung01 and TROPION-Lung-05 trials showed a survival advantage with dato-DXd vs docetaxel.
The National ICE-T Conference may inspire future collaboration between community and academic oncologists in the management of different cancers.
4 experts in this video