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Opinion|Videos|March 14, 2024

Rationale and Study Design of CIRCULATE-NORTH AMERICA in CRC

Author(s)John Strickler, MD, Aparna Raj Parikh, MD, MS , Stacey A. Cohen, MD

Arvind N. Dasari, MD, MS, gives an overview of the rationale and study design of the phase 2/3 CIRCULATE-NORTH AMERICA clinical trial.

Episodes in this series

A panel of 5 experts on colorectal cancer

EP. 1 Testing for MRD With ctDNA in Colorectal Cancer (CRC)

Arvind N. Dasari, MD, MS, an expert on colorectal cancer

EP. 2 Platforms for Testing MRD in CRC

A panel of 5 experts on colorectal cancer

EP. 3 MRD Testing Practices in Colorectal Cancer

Michael Foote, MD, an expert on colorectal cancer

EP. 4 Patient Profile 1: A 50-Year-Old With Stage III Colorectal Cancer

A panel of 5 experts on colorectal cancer

EP. 5 Prospective Trial Data on MRD Testing in Early-Stage CRC

A panel of 5 experts on colorectal cancer

EP. 6 COSMOS-CRC-03: ctDNA and Recurrence in Colorectal Cancer

Stacey Cohen, MD, an expert on colorectal cancer

EP. 7 Patient Profile 2: A 39-Year-Old Woman with High-Risk Stage II CRC

Aparna Parikh, MD, an expert on colorectal cancer

EP. 8 DYNAMIC Trial: ctDNA Analysis Guiding Adjuvant Therapy in Early-Stage CRC

A panel of 5 experts on colorectal cancer

EP. 9 Colorectal Cancer: Key Updates from GALAXY At ASCO GI 2024

Arvind N. Dasari, MD, MS, an expert on colorectal cancer

EP. 10 Rationale and Study Design of CIRCULATE-NORTH AMERICA in CRC

Stacey Cohen, MD, an expert on colorectal cancer

EP. 11 Initial Results from Phase 2 COBRA Study in Colorectal Cancer

Arvind N. Dasari, MD, MS, an expert on colorectal cancer

EP. 12 Patient Profile 3: A 62-Year-Old Woman with Colon Cancer

A panel of 5 experts on colorectal cancer

EP. 13 The Study Design and Early Findings from the INTERCEPT Study in CRC

A panel of 5 experts on colorectal cancer

EP. 14 BESPOKE CRC: The Impact of ctDNA-Guided Therapy in CRC

A panel of 5 experts on colorectal cancer

EP. 15 Future Perspectives on MRD Testing in Colorectal Cancer

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FDA OKs Subcutaneous Amivantamab in EGFR+ NSCLC

Imlunestrant Combo Will Not Be Pursued for FDA Approval in Breast Cancer

FDA Grants Regular Approval to Rucaparib in Metastatic CRPC

Pelareorep Exhibits Activity in Second-Line KRAS-Mutated Metastatic CRC

Gathering Data to Ascertain Biomarker Specificity in HER2– Breast Cancer