Taxotere for Anthracycline Refractory Advanced Breast Cancer

Publication
Article
Oncology NEWS InternationalOncology NEWS International Vol 5 No 7
Volume 5
Issue 7

COLLEGEVILLE, Penn--Rhône-Poulenc Rorer Inc.'s Taxotere (docetaxel) is now available for treatment of patients with locally advanced or metastatic breast cancer that has progressed during anthracycline-based therapy or relapsed during anthracycline-based adjuvant therapy.

COLLEGEVILLE, Penn--Rhône-Poulenc Rorer Inc.'s Taxotere(docetaxel) is now available for treatment of patients with locallyadvanced or metastatic breast cancer that has progressed duringanthracycline-based therapy or relapsed during anthracycline-basedadjuvant therapy.

In clinical studies, Taxotere has shown the highest response rateever (47%) for a single agent in this patient population at adose of 100 mg/m² given IV over 1 hour every 3 weeks, "avery convenient administration schedule," Howard A. BurrisIII, MD, of the Cancer Therapy and Research Center, San Antonio,said at a teleconference held to launch the new product.

Dr. Burris noted that "with a drug with this much impactin shrinking tumors in the advanced stage, the hope is that wewill eventually be able to bring it into stage I, II, and IIItreatment, and those clinical trials are ongoing."

The pivotal Taxotere trials were reported in this publicationin Nov 1995, page 1, and June 1996, page 16.

Newsletter

Stay up to date on recent advances in the multidisciplinary approach to cancer.

Recent Videos
Leading experts in the breast cancer field highlight the use of CDK4/6 inhibitors, antibody-drug conjugates, and other treatment modalities.
Patients with node-negative disease who are older and have comorbidities may not be suitable to receive CDK4/6 inhibitors.
An observed carryover effect with CDK4/6 inhibitors may reduce the risk of recurrence years after a patient stops treatment.
Breast oncologist Jade E. Jones, MD, says she tries to send patients with BRCA-mutant HR-positive TNBC to clinical trials that use PARP inhibitors.