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Opinion|Videos|April 25, 2025

Utilizing PSMA PET Imaging in Metastatic Prostate Cancer to Guide Treatment Strategies

Author(s)Jason Efstathiou, MD, DPhil, FASTRO, FACRO, Brandon Mancini, MD, MBA, FACRO , Comron Hassanzadeh, MD, MPH

Panelists discuss how PSMA PET imaging has significantly influenced prostate cancer management by enabling precise detection of metastatic lesions, thereby informing and altering treatment strategies. For instance, a study demonstrated that ^68Ga-PSMA-11 PET/CT impacted definitive radiation therapy (RT) planning in 16.5% of patients, leading to modifications in RT fields based on the imaging findings.

Episodes in this series

4 experts in this video

EP. 1 The Evolving Role of PSMA PET in Prostate Cancer Imaging and Management

4 experts in this video

EP. 2 PSMA PET Imaging Agents: Image Quality and Diagnostic Performance

4 experts in this video

EP. 3 Selecting the Optimal PSMA PET Imaging Agent: Clinical Considerations and Data-Driven Decisions

4 experts in this video

EP. 4 Imaging Quality in Prostate Cancer: Impact on Treatment Decision-Making

4 experts in this video

EP. 5 PSMA PET Imaging in Prostate Cancer Staging: Guiding Initial Diagnosis and Treatment Decisions

4 experts in this video

EP. 6 PSMA PET Imaging in Biochemical Recurrence: Clinical Approaches and Data-Driven Decisions

4 experts in this video

EP. 7 Role of PSMA PET Imaging in Guiding Surgical Treatment Decisions in Prostate Cancer

4 experts in this video

EP. 8 Leveraging PSMA PET Imaging in Posttreatment Response Assessment: Evolving Practices and Data Insights

4 experts in this video

EP. 9 Utilizing PSMA PET Imaging in Metastatic Prostate Cancer to Guide Treatment Strategies

4 experts in this video

EP. 10 Case Discussion: Integrating PSMA PET for Focal Boost Optimization

4 experts in this video

EP. 11 Evaluating the Role of Cu-PSMA PET Imaging in Prostate Cancer

4 experts in this video

EP. 12 Key Takeaways and Future Perspectives: PSMA PET Imaging in Prostate Cancer

Video content above is prompted by the following:

Present cases to highlight/illustrate the clinical application of PSMA PET imaging in guiding/informing treatment decisions.
Please share an example where PSMA PET led to expanding your radiation field.
What findings did PSMA PET imaging provide, and how did this help guide your decisions?
Briefly comment on this case and discuss implications for the practice setting.

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