Case Discussion: Integrating PSMA PET for Focal Boost Optimization

April 25, 2025

By Jason Efstathiou, MD, DPhil, FASTRO, FACRO
Brandon Mancini, MD, MBA, FACRO

Opinion

Video

Panelists discuss how PSMA PET imaging identified a region of high tracer uptake, guiding medical professionals to implement a focal radiation boost. This approach improved treatment precision and targeting of aggressive areas, highlighting the potential for personalized, effective therapies.

EP: 1.The Evolving Role of PSMA PET in Prostate Cancer Imaging and Management

EP: 2.PSMA PET Imaging Agents: Image Quality and Diagnostic Performance

EP: 3.Selecting the Optimal PSMA PET Imaging Agent: Clinical Considerations and Data-Driven Decisions

EP: 4.Imaging Quality in Prostate Cancer: Impact on Treatment Decision-Making

EP: 5.PSMA PET Imaging in Prostate Cancer Staging: Guiding Initial Diagnosis and Treatment Decisions

EP: 6.PSMA PET Imaging in Biochemical Recurrence: Clinical Approaches and Data-Driven Decisions

EP: 7.Role of PSMA PET Imaging in Guiding Surgical Treatment Decisions in Prostate Cancer

EP: 8.Leveraging PSMA PET Imaging in Posttreatment Response Assessment: Evolving Practices and Data Insights

EP: 9.Utilizing PSMA PET Imaging in Metastatic Prostate Cancer to Guide Treatment Strategies

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EP: 10.Case Discussion: Integrating PSMA PET for Focal Boost Optimization

EP: 11.Evaluating the Role of Cu-PSMA PET Imaging in Prostate Cancer

EP: 12.Key Takeaways and Future Perspectives: PSMA PET Imaging in Prostate Cancer

Video content above is prompted by the following:

Please share an example where you implemented a focal boost based on prostate-specific membrane antigen (PSMA) uptake intensity.
What findings did PSMA PET imaging provide, and how did this help guide your decisions?
Briefly comment on this case and discuss implications for the practice setting.

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