FDA Gives Full Approval to Pembrolizumab in dMMR/MSI-H Solid Tumors
Based on results from the phase 2 KEYNOTE-158, KEYNOTE-164, and KEYNOTE-051 trials, the FDA has given full approval to pembrolizumab for patients with microsatellite instability-high or mismatch repair deficient solid tumors.
Oncology On-The-Go Podcast: Integrative and Palliative Kidney Cancer Care
Santosh Rao, MD, discusses the formation of new guidelines informing the use of integrative oncology for patients with kidney cancer from the Society for Integrative Oncology.
FDA Grants Orphan Drug Designation to Tirabrutinib in Primary CNS Lymphoma
Investigators are assessing tirabrutinib, which received orphan drug designation from the FDA, as a treatment for patients with relapsed or refractory primary central nervous system lymphoma in the phase 2 PROSPECT study.
Oncology On-The-Go Podcast: Time to Treatment for Breast Cancer in Rural Populations
Minh-Tri Nguyen, MD, spoke with CancerNetwork® about differences between time to treatment, socioeconomic status, and clinical outcomes in rural and urban patients with breast cancer.
RUBY Trial Supports Addition of Dostarlimab to Chemo as SOC in Endometrial Cancer
Dostarlimab plus chemotherapy appears to improve progression-free survival vs placebo plus chemotherapy in patients with recurrent endometrial cancer in the phase 3 RUBY trial.
Pembrolizumab Combo Yields Benefits in pMMR/dMMR Advanced Endometrial Cancer
Pembrolizumab plus chemotherapy followed by maintenance pembrolizumab reduced the risk of death or disease progression in patients with mismatch repair proficient or deficient advanced endometrial cancer.
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