The Role of Menin Inhibitors in AML: Expert Perspectives

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A panel of experts on acute myeloid leukemia provide insights on how to diagnose acute myeloid leukemia as well as available and emerging treatment options with a focus on menin inhibitors.

The Role of Molecular Testing in Diagnosing Acute Myeloid Leukemia

EP. 1: The Role of Molecular Testing in Diagnosing Acute Myeloid Leukemia

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
June 22nd 2023

A panel of clinical experts provide insights about the importance of molecular and cytogenetic testing in diagnosing acute myeloid leukemia and in determining the best treatment plan.

When to Perform Molecular Testing in Relapsed AML

EP. 2: When to Perform Molecular Testing in Relapsed AML

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
June 22nd 2023

Harry P. Erba, MD, PhD, discusses the need to retest for mutations including IDH1, IDH2, FLT3, NPMI, and KMT2A rearrangement for patients with relapsed or refractory acute myeloid leukemia.

Barriers to Molecular Testing in AML

EP. 3: Barriers to Molecular Testing in AML

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
July 6th 2023

Eunice S. Wang, MD, offers an overview of common barriers to performing molecular testing in community practices, including uncertainty about which tests to perform and the wait times for results.

Treating Newly Diagnosed Acute Myeloid Leukemia

EP. 4: Treating Newly Diagnosed Acute Myeloid Leukemia

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
July 6th 2023

Daniel Pollyea, MD, MS, discusses how he assesses patients with newly diagnosed acute myeloid leukemia for the best first-line therapy, including the role of intensive induction chemotherapy.

Treatment Options for a Young, Fit Patient Newly Diagnosed with AML

EP. 5: Treatment Options for a Young, Fit Patient Newly Diagnosed with AML

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
July 13th 2023

The panel discuss the need for personalized treatment approaches for young, fit patients with newly diagnosed acute myeloid leukemia, as well as when transplant should be considered.

First-Line Treatment Options for NPM1-mutant AML

EP. 6: First-Line Treatment Options for NPM1-mutant AML

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
July 13th 2023

Eunice S. Wang, MD, shares first-line treatment approaches for patients with NPM1-mutant AML, discussing current clinical data.

First-Line Treatment Options for AML With KMT2a Rearrangements

EP. 7: First-Line Treatment Options for AML With KMT2a Rearrangements

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
July 20th 2023

Daniel Pollyea, MD, MS, discusses first-line treatment options for patients with AML with KMT2a rearrangements.

The Potential Role of Menin Inhibitors in the Front-Line Treatment of AML

EP. 8: The Potential Role of Menin Inhibitors in the Front-Line Treatment of AML

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
July 20th 2023

The expert panel review recently reported data from clinical trials evaluating menin inhibitors, including ziftomenib and revumenib, in the treatment of relapsed AML and how these treatments may fit into first-line settings.

Exploring Potential Combination Treatments for AML

EP. 9: Exploring Potential Combination Treatments for AML

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
July 27th 2023

Experts on acute myeloid leukemia share clinical insights on first-line combination therapies, including the potential role of menin inhibitors in this setting.

Menin Inhibitors in the Second-Line Treatment of AML

EP. 10: Menin Inhibitors in the Second-Line Treatment of AML

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
July 27th 2023

The expert panel discuss emerging data on menin inhibitors in the second-line treatment of AML, including an overview of the KOMET-001 trial evaluating ziftomenib.

The Role of Menin Inhibitors in the AML Treatment Armamentarium

EP. 11: The Role of Menin Inhibitors in the AML Treatment Armamentarium

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
August 3rd 2023

The panel of experts share their thoughts on where menin inhibitors will offer the most benefit in the overall treatment regimen for patients with AML.

Determining Which Patients Will Benefit the Most From Menin Inhibitor Treatment

EP. 12: Determining Which Patients Will Benefit the Most From Menin Inhibitor Treatment

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
August 3rd 2023

The expert panel provide clinical insights on which patients with AML may benefit the most from treatment with menin inhibitors.

Experts on AML

EP. 13: The AML Treatment Horizon

Naval Daver, MD;Harry P. Erba, MD, PhD;Dan Pollyea, MD, MS;Eunice S. Wang, MD
August 3rd 2023

Experts on acute myeloid leukemia offer closing thoughts and discuss emerging treatments in the field.

Menin Inhibitors in Acute Myeloid Leukemia: An Overview of “Encouraging” Early Data

EP. 14: Menin Inhibitors in Acute Myeloid Leukemia: An Overview of “Encouraging” Early Data

ONCOLOGY Staff
August 22nd 2023

Naval G. Daver, MD, reviewed current treatment options in acute myeloid leukemia, specifically the use of menin inhibitors in the space.