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Javier Sastre, MD, PhD

Articles by Javier Sastre, MD, PhD

UFT Plus or Minus Calcium Folinate for Metastatic Colorectal Cancer in Older Patients

ByEduardo Diaz-rubio, MD, PhD,Javier Sastre, MD, PhD,Albert Abad, MD, PhD,Matilde Navarro, MD,Enrique Aranda, MD, PhD,Alfredo Carrato, MD, PhD,Manuel Gallén, MD,Eugenio Marcuello, MD,Julio Rifá, MD,Tomeu Massuti, MD,Andrés Cervantes, MD, PhD,Antonio Antón, MD, PhD,Carlos Fernandez-martos, MD

Two studies were carried out to determine the activity and evaluate the toxicity of oral chemotherapy with uracil and tegafur in a 4:1 molar ratio (UFT) plus or minus calcium folinate in elderly patients with advanced colorectal

UFT Plus Oral Folinic Acid as Therapy for Metastatic Colorectal Cancer in Older Patients

ByAlbert Abad, MD, PhD,Cristina Martín, MD,Matilde Navarro, MD,Javier Sastre, MD, PhD,Eduardo Diaz-rubio, MD, PhD,Eugenio Marcuello, MD,Enrique Aranda, MD, PhD,Manuel Gallén, MD,Carlos Fernandez-martos, MD

The oral fluoropyrimidines have proved to be active in colorectal cancer in Japan and, recently, in the United States and Europe. Continuous oral administration simulates protracted fluorouracil (5-FU) continuous

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