Paclitaxel as First-Line Treatment for Metastatic Breast Cancer
ByJames F. Bishop, MD, MBBS,Martin H. Tattersall, MD, MB,Joanna Dewar, MBBS,Guy C. Toner, MD, MBBS,Ian N. Olver, MD, MBBS,Stephen Ackland, MBBS,Ian Kennedy, MBBS,David Goldstein, MBBS,Howard Gurney, MBBS,Euan Walpole, MBBS,John Levi, MD, MBBS,Jennifer Stephenson, MSc
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When administered as a single agent in pretreated patients with advanced breast cancer, paclitaxel (Taxol) exhibits remarkable antitumor activity. This trial was undertaken to compare paclitaxel with standard