Author | Jennifer Wu, MD

Articles

Targeted Therapy: Its Status and Promise in Selected Solid Tumors Part II

November 16, 2012

This second article in our two-part series on targeted therapies in solid tumors covers the emergence of targeted therapies for the treatment of two common malignancies: lung cancer and breast cancer.

Targeted Therapy: Its Status and Promise in Selected Solid Tumors Part I

October 23, 2012

We describe areas where major inroads were initially achieved by targeting angiogenesis and by unraveling pathways in the heterogeneous tumors of mesenchymal origin-spurred by the identification of c-Kit–activating mutations in GIST and the regressions that ensued when tumors harboring these mutations were exposed to the tyrosine kinase inhibitor imatinib (Gleevec).