Author | M. H. Oosterwijk, PhD

Articles

Genetic Counseling in Hereditary Nonpolyposis Colorectal Cancer

January 01, 1996

Recent identification of gene mutations responsible for hereditary nonpolyposis colorectal cancer (HNPCC) has made possible the presymptomatic diagnosis of at-risk family members. If DNA testing shows that a family member is a gene carrier, that individual's lifetime cancer risk is approximately 90%. If the test is negative, the family member's cancer risk drops to that of the general population.