Cutaneous T-Cell Lymphoma: Pathogenesis and TreatmentByMichael Girardi, MD,Richard L. Edelson, MDJuly 1st 2000Cutaneous T-cell lymphoma (CTCL) is a malignancy of a distinctive subset of T-helper cells designated “cutaneous T cells” because of their central role in the normal functioning of the skin immune system. Guided by