P. D. Boasberg | Authors

Thalidomide-Induced Cessation of Weight Loss and Improved Sleep in Advanced Cancer Patients With Cachexia

November 01, 2000

The cachexia of malignancy is considered mediated through excess production of tumor necrosis factor–alpha and other cytokines. Thalidomide (Thalomid), a sedative/hypnotic, has been shown to inhibit tumor necrosis factor–alpha production.