Author | Pierfranco Conte, MD

Articles

New Combinations With Epirubicin in Advanced Breast Cancer

May 01, 2001

Several trials have shown that anthracyclines and taxanes can be combined to achieve response rates ranging from 70% to 90%, with complete responses ranging from 19% to 41%. In an attempt to increase the activity while

Epirubicin/Taxane Combinations in Breast Cancer: Experience From Several Italian Trials

May 01, 2001

Doxorubicin/paclitaxel (Taxol) combinations are very active in advanced breast cancer, with objective response rates up to 90%, but have shown a high incidence of cardiotoxicity. A phase I/II trial replacing

Gemcitabine/Epirubicin/Paclitaxel Trials in Advanced Breast Cancer

February 01, 2001

Numerous trials have shown that the pharmacokinetic interferences of epirubicin (Ellence)/paclitaxel (Taxol) combinations produce less pharmacodynamic effect than doxorubicin/paclitaxel regimens. Paclitaxel is more easily

Paclitaxel Plus Epirubicin in Advanced Breast Cancer

January 01, 1998

This phase I-II study aimed to determine the maximum tolerated dose (MTD) of paclitaxel (Taxol), infused over 3 hours, when combined with a fixed dose (90 mg/m²) of epirubicin. Other aims were to investigate the combination’s