Author | Siegfried Seeber, MD, PhD

Articles

Paclitaxel and UFT Plus Oral Calcium Folinate in Pretreated Metastatic Breast Cancer

July 01, 1999

ByUte Klaassen, MD

David Borquez, MD

Stephanie Lang, MD

Carsten Oberhoff, MD

Andreas Harstrick, MD

Siegfried Seeber, MD, PhD

Steven Benner, MD

This phase I study was designed to determine the maximum tolerated dose (MTD) and dose-limiting side effects of combination treatment with paclitaxel (Taxol) and UFT (uracil and tegafur in a 4:1 molar ratio) plus oral

Metastatic Breast Cancer: Treatment With Fluorouracil-Based Combinations

September 02, 1997

ByUte Klaassen, MD

Siegfried Seeber, MD, PhD

During the 1990s, one in nine women in the western world will be diagnosed with breast cancer, and more than 58,000 will die of the disease each year in Europe alone. Recent changes in the primary therapy of operable

Infusional 5-FU, Folinic Acid, Paclitaxel, and Cisplatin for Metastatic

April 01, 1997

ByUte Klaassen, MD

Hans Jochen Wilke, MD

Siegfried Seeber, MD, PhD

Our phase II study results demonstrating high efficacy and low toxicity for a weekly schedule of high-dose, 24-hour infusional 5-fluorouracil(5-FU)/folinic acid (HD5-FU/FA) in intensively pretreated patients with metastatic